VITALITY AFTER SEVERE INJURY.

Patient after Severe Head Injury

Background: The pharmacodynamic differences in time to onset and dissipation of effect of sufentanil, fentanyl, and alfentanil probably result from different rates of blood-brain equilibration. The authors investigated this hypothesis in humans. Methods: After simultaneous central venous bolus application of sufentanil (10 pg), fentanyl (100 pg), and alfentanil (1,000 pg), arterial and jugular ...

P24: Minimally Conscious State Improvements with Thalamic Ventralis Intermedius Nucleus Stimulation after Severe Traumatic Brain Injury

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Working memory after severe traumatic brain injury.

The aim of the present study was to assess the functioning of the different subsystems of working memory after severe traumatic brain injury (TBI). A total of 30 patients with severe chronic TBI and 28 controls received a comprehensive assessment of working memory addressing the phonological loop (forward and backward digit span; word length and phonological similarity effects), the visuospatia...

Survival after severe intrathoracic electrical injury.

Cerebral endothelial damage after severe head injury.

We demonstrate that in head injuries the degree of cerebral endothelial activation or injury depends on the type of brain injury and the patients age, and that in severe head injuries measuring the serum levels of thrombomodulin (TM) and von Willebrand factor (vWF) is useful in evaluating cerebral endothelial injury and activation. The values of vWF in the cases of focal brain injury were signi...